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Panama City to Miami

Classic Panama Canal

fares from $3,499 per guest

11-Day Voyage

Sirena

Feb
18
2025
TO
Mar
1
2025

Special Offer

With simply MORE*, our new valuable offer, enjoy 2 for 1 Cruise Fares, Free Roundtrip Airfare and Airport Transfers* plus:

FREE $600 simply MORE Shore Excursion Credit
FREE Champagne, Wine & More
FREE Gourmet Specialty Dining
FREE Unlimited WiFi
Amenities are per stateroom

View All Offers


You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action.